Yes, it is possible, and Xishom is correct about the fans. I use two box fans stacked on top of one another pointed outside. It sucks air from under the door of the room in and pushes everything out. Also, you can open the door for a couple of seconds and not worry about the fumes spreading far.Has anyone here done resin/bondo/fiberglass work inside their house that can tell me how big a problem fume leakage might be?
I would also suggest that you build a hot box for your work after you are done. It is much easier and cheaper than keeping the room at a constant temperature. A hot box is basically a costumers easy bake oven. You need a plastic tote that is twice as large as your largest project. Line it with aluminum foil to help insulate it. Put a light inside of it. Specifically, you need a normal light bulb, not a CFL or halogen. If you wanted to get really fancy, get a low-intensity heat lamp.
All you need to do is drop whatever project you are doing into the box, turn on the lamp, and close the lid. The light will keep the temperatures constant inside the box. The reason for the space is so you don't have to worry about the light melting or warping anything (project or box).
I live in Northern Oregon, and this is what I have been doing for quite a while. It works quite well, even when it is snowing outside. Then again, I built a work desk with a shroud and clear acrylic view shield so I don't freeze my cod piece off while working in the room and it has the same fan setup, but in a smaller scale.
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See my next post HERE. It might answer some questions.And for the paint job in the end, what steps do I take? I have heard so many different techniques but I don't know which one would be the best. Thanks for your help!!